Some Mr. Men and Little Misses are related to each other, and also have mentioned unseen members too.
With Each Other[]
- Little Miss Twins — The book is mainly about two twin sisters.
- Little Miss Whoops — Mr. Bump is Miss Whoops's brother.
- Little Miss Chatterbox — Mr. Chatterbox is Miss Chatterbox's brother.
- Mr. Fussy - Mr. Fussy and Mr. Clumsy are cousins.
- Hello, Pizza Express?- Mr. Rush is related to Mr. Busy and Mr. Fussy.
- Little Miss Fabulous - Little Miss Splendid and Little Miss Fabulous are cousins
Offscreen/Minor Characters[]
- Mr. Mean - Mr. Mean has a brother whom he only gives coal to.
- Little Miss Princess - Little Miss Princess has a mother and father who are the Queen and King of Misterland.
- Mr. Chatterbox Loses His Voice — Mr. Chatterbox had a father, a grandfather, and a great grandfather who all wore green hats.
- Little Miss Splendid's Gift - Miss Splendid has cousins in Seatown.
- Hello, Pizza Express? - Miss Chatterbox has an aunt, a cousin, an uncle, and a cousin by marriage who has red hair.
- Little Miss Star Goes to Jollywood - Mr. Forgetful asks about Miss Star's great grandmother's Christian name.
- Paint — Miss Chatterbox had an uncle who couldn't stand still while being painted due to having hiccups.
Onscreen/Minor Characters[]
- Sneezes and Hiccups - Mr. Rude's family appears at the Dillydale Glee Club concert.