- Mr. Tickle: A dark stripe is added to his hat, and he can actually shrink his arms at will. His body shape also changed into a perfect circle, rather than an oval.
- Mr. Bounce: His hat is now dark pink, with a lighter pink stripe added to it.
- Mr. Happy: He is less round.
- Mr. Nos(e)y: Color is changed to lime green, body shape now looks like a pear, and has an orange oval nose. He also wears a black necktie.
- Mr. Bump: Number of bandages is reduced to five.
- Mr. Messy: Body is more solid and has a unibrow. He also wears messy blue sneakers.
- Mr. Small: Orange seed-shaped body with a large black top hat and sneakers.
- Mr. Nervous: Purple egg-shaped body and a turquoise nose with lines. He wears black shoes and a pair of glasses.
- Mr. Grumpy: His nose is now oval-shaped with lines on it, he has gained a uni brow, and he now has a crooked hat with a lighter green stripe.
- Mr. Tall: He has gained a brown fedora hat.
- Mr. Fussy: His shoes are now pointed, he now has a bow tie, a pair of glasses, and his mustache is neater. In season 1, his name was changed to Mr. Persnickety, and he was a lighter shade of green, but in season 2, he got his old name and color back.
- Mr. Strong: He is now an upside-down triangle, he now has a belt, and has larger biceps to emphasis his personality.
- Mr. Noisy: He is now usually seen with a megaphone to emphasis his personality.
- Mr. Quiet: He is now an oval-shape, light blue, number of hairs was reduced to 2, and he now has a uni brow.
- Mr. Lazy: He is now green, skinny, with socks and sandals, a darker green oval-shaped nose, and a magenta messenger hat.
- Mr. Funny: Nose is larger and has lines, large clown shoes, a bow tie, and no gloves.
- Mr. Rude: He has traded his top hat for a pair of brown shoes that look like Mr. Noisy's, except smaller. Though he did wear his hat twice in season 2.
- Little Miss Naughty: She now has a lime-green bow, nose is now pink, has pinker cheeks, and she now has pink puffy hair.
- Little Miss Whoops: She is now a lighter blue, has no hair, no bandages, a pink bow, and round glasses.
- Little Miss Sunshine: Hair is now a darker yellow.
- Little Miss Helpful: Now has pigtails and a green fanny pack.
- Little Miss Bossy: Now a darker shade of blue and the flower on her hat no longer has the stem
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